Journal: Indian Journal of Pharmacology

Article Title: Nephroprotective potential of syringic acid in experimental diabetic nephropathy: Focus on oxidative stress and autophagy

doi: 10.4103/ijp.ijp_671_22

Figure Lengend Snippet: (a) Representative Immunoblot images demonstrating the effect of SYA on NQO1, Nrf2, Atg7, and p62 in NRK 52E cells challenged with high glucose. (b) Immunofluorescence images of NRK 52E cells immunostained with LC-3 and Lysotracker red. (c) Immunofluorescence images depicting immunostaining of Nrf2 in NRK 52E cells. The values are expressed in terms of mean ± SEM ( n = 3). NC = Normal NRK 52E cells, NC + SYA-20: Normal NRK 52E cells treated with SYA at 20 μM HG-NRK 52E cells challenged with 30 mM glucose. SYA = Syringic acid, LC: Light chain, SEM = Standard error of the mean, NRK: Normal rat kidney, Nrf2 = Nuclear factor erythroid 2-related factor 2

Article Snippet: NRK 52E cell (rat renal epithelial cells) cell line was obtained from National Centre for Cell Science, Pune and maintained in Dulbecco's Modified Eagle Medium (glucose concentration 1 g/L) accompanied with 10% Fetal bovine serum, streptomycin/penicillin (1%) at 37°C with 95% air and 5% CO2.

Techniques: Western Blot, Immunofluorescence, Immunostaining

Journal: Advances in Pharmacological and Pharmaceutical Sciences

Article Title: Potential Nephroprotective Effect of Kaempferol: Biosynthesis, Mechanisms of Action, and Clinical Prospects

doi: 10.1155/2024/8907717

Figure Lengend Snippet: The role of kaempferol in alleviating renal diseases.

Article Snippet: Renal fibrosis , NRK-52E cells , UUO-induced renal fibrosis in Sprague-Dawley rats , Activation of the BMP-7-Smad1/5 signaling pathway , 30, 60, and 90 mg/kg, and 0.5, 1, 5, 10, 20, 40, 80, 100, and 200 μ M , [ ] .

Techniques: In Vitro, In Vivo, Inhibition, Membrane, Expressing, Activation Assay, Protein-Protein interactions, Migration